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KMID : 0363219770150040511
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Korean Journal of Dermatology
1977 Volume.15 No. 4 p.511 ~ p.515
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A Case Report of Amelanotic Melanoma
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金重基/Kim, Joong-Gie
晋洪商/趙鼎九/Chin, Hong-Sang/Cho, Chung-Koo
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Abstract
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A case of amelanotic melanoma developed on a 19 years old boy was reported. Since the identification of amelanotic melanoma, there were few reports about the tumor but none in Korea. In this case, the histologic findings showed ulceration of the epidermis and irregular junctional activity, and in the dermis, there showed alveolar formation and nevus cell nest like cell ma´;ses. And in the deep dermis, the loss of dermal stroma with numerous bizzare giant cells and variable sized, hyperchromatic; pleomorphic, mitotic figures were also seen. Strikingly, there were no melanin pigments in H-E stain as well as in Masson-Fontana stain, which was thought to be a amelanotic melanoma.
The patient was treated with B.C.G. vaccination by intralesional and hypodermic injection, on the lesion and on both anterior thigh, respectively.
One year after treatment, the lesion was markedly improved with only scar formation on previously ulcerated lesion.
The patient shall be followed up continuously.
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